As an indispensable excipient in pharmaceuticals, the safety of empty capsules is directly related to the life and health of patients. However, what are the serious consequences if raw material suppliers are not strictly audited during the production process, or if raw materials are not subjected to incoming inspection? The most direct and fatal consequence is that the heavy metal chromium content in the capsule shells exceeds the safety limit (>2ppm).
Ekisooka, obutaba na kubala ebitabo by’abagaba ebintu kiggulawo oluggi lw’okuyingira kw’ebintu ebisookerwako eby’omutindo ogwa wansi. Mu mulimu gw'okukola gelatin, nga bavugibwa okunoonya amagoba amangi, abamu ku bakola ebintu abatalina mpisa bayinza okukozesa kasasiro w'amaliba, amanyiddwa ennyo nga "blue alum skin" okufumba gelatin mu makolero. Bbeeyi ya gelatin eno ey’amakolero eri wansi nnyo okusinga eya gelatin ow’eddagala, naye asibuka mu mulimu gw’okusiiga amaliba. Okuva okusiiga enviiri bwe kuzingiramu okukozesa ennyo ebirungo ebirimu chromium-, ekirungo kya chromium mu gelatin w’amakolero kiri waggulu nnyo. Awatali kubala nsibuko enkakali n’okukakasa mu kifo -abagaba eddagala, abakola eddagala basanga obuzibu okuzuula obutali mu mateeka bw’ensibuko y’ebintu ebisookerwako, bwe batyo mu butamanya bakozesa ebintu bino eby’omutindo ogwa wansi.
Ekirala, okubuuka okukebera ebintu ebisookerwako kisobozesa ebintu ebisukka omutindo okutuuka butereevu ku balwadde. Okusinziira ku biragiro by’ekitongole kya Chinese Pharmacopoeia, chromium ali mu capsules empty terina kusukka 2ppm. Eno layini emmyufu enkakali ey’obukuumi. Wabula singa kkampuni ebuuka omutendera gw’okukebera omutindo ng’emaze okugula ebintu ebisookerwako, tekisoboka kuzuula bucaafu bwa byuma bizito obutalabika na maaso. Gelatin eno eya chromium omungi-bwe ekolebwa ebisusunku bya kkapu n'ejjula eddagala, efuuka "ssukaali" asiigiddwa obutwa.
Obulabe bw’ekirungo kya chromium ekisusse eri obulamu bw’omuntu tebuyinza kutunuulirwa wansi. Chromium akuŋŋaanyizibwa mu mubiri, ate naddala chromium ow’ekika kya hexavalent alina obutwa bungi. Okumira okumala ebbanga eddene kisobola okwonoona ebitundu by’omubiri ng’ekibumba n’ensigo era kiyinza n’okuleeta akabi k’okuleeta kookolo. Wadde ng’okumira omulundi gumu kiyinza obutaleeta butwa bwa maanyi, okumala ebbanga eddene-okukozesa eddagala eryo erya kkapu awatali kubuusabuusa kuba kuziika bbomu ey’ekiseera munda mu mubiri.
Mu bufunze, abagaba ebintu abatabaliriddwa oba abatagezesebwaebikozesebwa ebisookerwakobye bikolo ebivaako chromium asusse mu kkapu. Kino si kulemererwa kulondoola mutindo gwokka wabula n’obutafaayo ku bulamu bw’abaguzi. Ebitongole ebikola eddagala birina okugoberera omutindo ogusookerwako, okukuuma ennyo emiryango gy’okubala ebitabo n’okugezesa, n’okukakasa nti buli kkapu emu terimu bulabe era nnongoofu. Bwoba waliwo ekibuuzo kyonna ku capsules empty, Mwaniriziddwa okukwatagana ne KornnacCaps.
